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Predicting dementia from spontaneous speech using large language models

We demonstrate that the text embedding can be reliably used to (1) distinguish individuals with AD from healthy controls, and (2) infer the subject’s cognitive testing score, both solely based on speech data. We further show that text embedding considerably outperforms the conventional acoustic feature-based approach and even performs competitively with prevailing fine-tuned models. Together, our results suggest that GPT-3 based text embedding is a viable approach for AD assessment directly from speech and has the potential to improve early diagnosis of dementia.


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