Researchers from the Stanford Center for Digital Health (CDH), Dr. Ashish Sarraju, Clark Seninger, Dr. Mintu Turakhia, and Dr. Rajesh Dash, set out to validate the feasibility of a completely virtual, decentralized clinical trial for cardiovascular interventions in a decentralized trial in atrial fibrillation patients (DeTAP) by integrating a range of individual digital health technologies for physiologic measurements among atrial fibrillation patients on oral anticoagulation (OAC) therapy. To date, no large-scale phase 3 cardiovascular trial has employed a 100% remote, decentralized protocol including physiologic measurements.
Their hypothesis? The decentralized protocol may achieve more rapid recruitment, robust protocol adherence, and higher participant engagement.
